Infection is acquired by eating undercooked freshwater fish. Infection with the trematode clonorchis sinensis is the most common human fluke infection in east asian populations. This fluke is quite common in china, japan, korea, taiwan and vietnam among others. Low divergence of clonorchis sinensis in china based on. Hal ini dipilih seperti contoh tipe untuk trematoda karena struktur kurang spesial. China, especially in the northeastern provinces of heilongjiang and jilin ministry of health china, 2005, as well as in neighbouring regions of both north and south korea hotez, 2003.
During the 2 past decades, many reports regarding imaging findings of clonorchiasis were introduced. Symptoms of clonorchiasis are related to worm burden. Clonorchis sinensis was named after that the worm was discovered in the bile duct of a chinese carpenter in calcutta, a harbor city of india, in 1874. The pathology of clonorchis sinensis infestation of the liver. Cacing clonorchis atau chinese liver fluke atau clonorchis sinensis hidup dalam hati manusia, daur hidupnya hampir sama dengan fasciola, hanya inang perantaranya adalah ikan air tawar. Clonorchis sinensis, also known as the chinese liver fluke, belongs to the family opisthorchiidae, and is one of the most important foodborne parasites, endemic in eastern asian countries, including china, korea, vietnam, thailand and the far east regions of russia. Clonorchiasis, or chinese liver fluke disease, is caused by infection with clonorchis sinensis.
Identification and characterization of clonorchis sinensis cathepsin. Clonorchis merupakan anggota dari trematoda platyhelminthes. Trematode parasites of the genera clonorchis, opisthorchis and metorchis, commonly referred to as liver flukes, are transmitted to humans and other mammals by the ingestion of fish infected with their larval stages which. Human clonorchiasis is a prevailing foodborne disease caused by clonorchis sinensis infection. Trematode parasites of the genera clonorchis, opisthorchis and metorchis, commonly referred to as liver flukes, are transmitted to humans and other mammals by the ingestion of fish infected with their larval stages which ultimately come from snails infected due to excreta. The trematode clonorchis sinensis chinese or oriental liver fluke is an important foodborne pathogen and cause of liver disease in asia. Clonorchis sinensis introduction clonorchis sinensis, also known as the chinese liver fluke is a narrow elongate liver fluke found in the far east.
Free publisher full textpmc free full textpmc free pdf. Chang department of pathology, university of hong kong. Clonorchis sinensis infestation promotes threedimensional. Diagnosis is by identifying eggs in the feces or duodenal contents.
Manusia terinfeksi melalui makanan ikan tawar mentah yang mengandung kista cacing tersebut. Clonorchis sinensis, the chinese liver fluke, is a liver fluke belonging to the class trematoda, phylum platyhelminthes. Department of pathology and bacterilogy, university of hong kong. This segregation is consistent with the broader natural distribution of the two species. Opisthorchis sinensis clonorchis sinensis adalah cacing hati pada manusia, dan juga terdapat pada kucing dan anjing, sebagai tuan rumah yang berfungsi seperti gudang. Clonorchiasis is a common disease in china, vietnam, korea, and japan and is acquired by. Linking to a nonfederal website does not constitute an endorsement by cdc or any of its employees of the sponsors or the information and products presented on the website. Key method a total of 347 residents showed positive stool results for clonorchis sinensis eggs in a village in northeastern china, and were treated with praziquantel. Since that time, new data have become available, these have been incorporated in the monograph, and taken into consideration in the present evaluation.
Clonorchis sinensis, the chinese or oriental liver fluke, is an important human parasite and is widely distributed in southern korea, china including taiwan, japan, northern vietnam and the far eastern part of russia. Current status of clonorchis sinensis and clonorchiasis in. Clonorchis sinensis introduction to medical parasitology. Clonorchis sinensis ova in bile juice cytology from a. Microscopic examination of gallbladder stones improves. It parasitises the biliary duct in humans who become infected by eating raw or undercooked fish.
The chinese liver fluke clonorchis opisthorchis sinensis is widely distributed in the far east. Pubmed journal articles for clonorchis sinensis were found in prime pubmed. Clonorchiasis occurs in all parts of the world where there are asian immigrants from endemic areas. Infection is usually acquired by eating undercooked freshwater fish. Humans become infected by eating raw, undercooked, dried, salted, or pickled fish. Nama lain parasit ini adalah opisthorchis sinensis atau the chinese liver fluke.
Prevalence and intensity of clonorchis sinensis metacercariae in. Clonorchiasis is an infectious disease caused by the chinese liver fluke, clonorchis sinensis, and two related species. Links with this icon indicate that you are leaving the cdc website the centers for disease control and prevention cdc cannot attest to the accuracy of a nonfederal website. Production and deformation of clonorchis sinensis eggs during in. Clonorchiasis is an important foodborne trematodiases in asia, caused by chronic infection with clonorchis sinensis 1, 2. Nevertheless, they are often underestimated compared to other, better known neglected diseases in spite of the fact that many millions of humans are infected and hundreds of millions at risk. Dpdx is an educational resource designed for health professionals and laboratory scientists. Current status and perspectives of clonorchis sinensis and. Pdf hepatitis b and c virus, clonorchis sinensis for the. Clonorchis sinensis family opisthorchiidae is an important foodborne parasite that has a major socioeconomic impact on 35 million people predominantly in china, vietnam, korea and the russian. Clonorchis sinensis, dipylidium caninum, dan toxocara cati bersifat zoonotik. An enzymelinked immunosorbent assay elisa was developed to replace the usual intradermal test, and its performance in an area of endemicity was evaluated. Clonorchiasis is a common infection of dogs and other fisheating carnivores reservoir final hosts in china, the democratic peoples republic of korea, the republic of korea and viet nam. To improve the rate of detection of clonorchis sinensis infection, we compared different specimens from patients with cholecystolithiasis.
Clonorchis sinensis adalah salah satu trematoda hati yang bersifat hermaprodit yang dapat menimbulkan penyakit clonorchiasis. Clonorchis sinensis opisthorchis viverrini and clonorchis sinensis were considered by a previous iarc working group in 1994 iarc, 1994. Clonorchis sinensis an overview sciencedirect topics. Clonorchis sinensis is a fishborne trematode that inhabits the bile duct of mammals including humans. In 1874, a 20 year old chinese carpenter was admitted to the medical college hospital. Hepatitis b and c virus, clonorchis sinensis for the risk of liver cancer. Clonorchiasis is infection with the liver fluke clonorchis sinensis. Eating raw or halfcooked fresh water fish and shrimps human liver fluke disease clonorchis and opistorchis are quite similar causing similar disease. The relationship between primary carcinoma of the liver and infestation with clonorchis sinensis hou pao. Opisthorchis viverrini and clonorchis sinensis were considered by a previous iarc working group in 1994. Clonorchiasis is a known risk factor for the development of cholangiocarcinoma, a neoplasm of the biliary system.
Cholangiocarcinoma, clonorchiasis, clonorchis sinensis. The human and animal reservoir hosts dogs, pigs, cats and rats acquire the. In humans, it infects the common bile duct and gall bladder, feeding on bile. Pdf changes in sonographic findings after treatment of. Clonorchis sinensis is the major liver fluke found in p. The relationship between primary carcinoma of the liver.
Feces, gallbladder bile, and gallbladder stones collected from 179 consecutive patients with cholecystolithiasis underwent microscopic examination, and according to the results, 30 eggpositive and 30 eggnegative fecal, gallbladder bile, and. Approximately 35 million people are infected with c. Prime pubmed clonorchis sinensis journal articles from pubmed. Immunological analysis of opisthorchis and clonorchis. Clonorchiasis, chronic infection caused by clonorchis sinensis, or liver fluke, a parasitic worm some 10 to 25 mm 0. Untuk menghindari penyakit ini, masaklah ikan air tawar secara sempurna karena jika terkena penyakit ini akan menyebabkan kerusakan hati yang. We would like to show you a description here but the site wont allow us. Cdc clonorchis biology centers for disease control. Clonorchis sinensis is still a common parasite in south korea. Of them, 2 patients underwent abdominal sonography both before and 1 year after treatment, and the changes in sonographic findings of 83 cured subjects were compared. Clonorchis sinensis, an oriental liver fluke, as a human biological.
Clonorchis sinensis is known to be widely distributed in northern provinces, whereas o. The basic imaging finding of clonorchiasis is diffuse dilatation of the peripheral intrahepatic bile ducts, without dilation of the large. Clonorchis sinensis and clonorchiasis pdf free download. Clonorchis sinensis the oriental or chinese liver fluke clonorchis sinensis adult clonorchis sinensis egg 1. Humans become infected by eating raw, undercooked, dried, salted, or pickled fish containing encysted metacercariae. Images in clinical medicine from the new england journal of medicine clonorchis sinensis. The pathology of clonorchis sinensis infestation of the liver pao.
Clonorchiasis wikipedia bahasa indonesia, ensiklopedia bebas. Clonorchis sinensis, the etiological agent of clonorchiasis, is the most endemic fishborne zoonotic liver fluke that causes a heavy socioeconomic burden in south asia 1. Dogs and cats are the most important reservoir hosts. Clonorchiasis, clonorchis sinensis, diagnosis, pathogenesis, omics, prevention. Clonorchis sinensis, opisthorchis viverrini, and o. Symptoms include fever, chills, epigastric pain, tender hepatomegaly, diarrhea, and mild jaundice. Clonorchis sinensis, opisthorchis spp, and metorchis spp. Although man is the main host, the parasite also infects cats, dogs and other fisheating carnivores which probably serve as reservoirs of human infection.
The infection status of clonorchis sinensis metacercariae csmc was examined in freshwater fish from a highly prevalent site, wicheon a. Although this infection is associated with obstructive jaundice or choledocholithiasis, portal vein thrombosis has not been reported. Clonorchiasis adalah penyakit menahun yang menyerang bagian saluran antara hati dan empedu, disebabkan oleh cacingcacing clonorchis sinensis. Clonorchis wikipedia bahasa indonesia, ensiklopedia bebas. Immunological analysis of opisthorchis and clonorchis antigens volume 64 issue 2 s. Human eats undercooked fish containing the metacercaria. Among several diagnostic tools for clonorchiasis clonorchis sinensis infection, radiologic examinations are commonly used in clinical practices. Performance of an enzymelinked immunosorbent assay for. Clonorchis sinensis infection, but that detecting igm antibody had not. The kits detecting igg antibody also showed high sensitivity in heavy infection intensity.
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